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TNM Staging System for Mesothelioma Proposed

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A clinicopathologic staging system for diffuse malignant peritoneal mesothelioma (DMPM) stratifies survival through tumor-node-metastasis (TNM) criteria. Using prospectively collected data from 8 institutions, the developers identified 3 prognostic factors independently associated with survival: peritoneal cancer index, lymph node status, and extra-abdominal metastasis. The developers based the TNM system on these 3 factors, which they identified as influenced by disease progression from a set of 7 factors associated with improved survival in their univariate analysis of the data.

 

The developers, on behalf of the Peritoneal Surface Oncology Group, published their findings in the May 1 edition of Cancer (http://onlinelibrary.wiley.com/doi/10.1002/cncr.25640/abstract;jsessionid=422F98BF71C2B599BFE1AC4C20045F80.d02t03?systemMessage=Wiley+Online+Library+will+be+disrupted+14+May+from+10-12+BST+for+monthly+maintenance).

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