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TOP - February 2017, Vol 10, No 1

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) occur mainly in older patients, who are likely to have several comorbidities and who often are unable to receive aggressive drug therapies, such as alkylating drugs, which are typically used for patients with CLL or SLL. Read More ›

Elderly patients with chronic lymphocytic leukemia (CLL) and younger patients with comorbidities often receive treatment with chlorambucil despite the relative low response rates. Read More ›

In 2016, approximately 18,960 Americans were estimated to be diagnosed with chronic lymphocytic leukemia (CLL), and 4660 were estimated to die from the disease. Read More ›

It is estimated that 18,960 new cases of chronic lymphocytic leukemia (CLL) were diagnosed in 2016, and 4660 deaths. Read More ›


Delirium Symptoms More Severe in Patients Treated with Antipsychotics
Adult hospice and palliative care patients with hyperactive delirium symptoms who were given risperidone or haloperidol had greater delirium symptoms at 72 hours than those given placebo. Read More ›

Transitioning from Inpatient to Outpatient Chemotherapy Saves Money, Increases Patient Satisfaction
Inpatient chemotherapy is often considered a financial loss, and according to Ali McBride, PharmD, MS, BCPS, BCOP, Clinical Coordinator, Hematology/Oncology, The University of Arizona Cancer Center, Tucson, transitioning chemotherapy to the outpatient setting can be beneficial to patients and providers. Read More ›

Mounting Evidence for Ki67 as Independent Prognostic Marker
Several studies have shown that Ki67 is an independent prognostic factor in patients with breast cancer, and Ki67 is included in the Oncotype DX test that estimates the likelihood of breast cancer recurrence and the need for chemotherapy. Read More ›


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