Articles
Pharmacists should caution fellow healthcare providers about the potential dangers of tablet splitting, according to a new study. The researchers found that this common practice results in wide dose deviations, which could have serious clinical consequences for tablets that have a narrow margin between therapeutic and toxic doses.
The study, published in the January issue of the Journal of Advanced Nursing, showed that nearly a third of the split fragments deviated from recommended dosages by 15% or more.
By Debra Wood
Adult survivors of childhood acute lymphoblastic leukemia (ALL) treated with dexamethasone may have greater risk for neurocognitive impairment and poor emotional regulation than patients treated with prednisone, and they exhibited symptoms of physical stress. Read More ›
By Debra Wood
Almost half of the cancer patients in a recent study did not receive any thromboprophylaxis during hospitalization, even though cancer and its treatment increases the risk for deep-vein thrombosis (DVT) and pulmonary embolism (PE) and three professional organizations—the American College of Chest Physicians, the American Society of Clinical Oncology, and the National Comprehensive Cancer Network—have issued guidelines recommending DVT prophylaxis. Read More ›
Adult survivors of childhood acute lymphoblastic leukemia (ALL) treated with dexamethasone may have greater risk for neurocognitive impairment and poor emotional regulation than patients treated with prednisone, and they exhibited symptoms of physical stress.
Read More ›Almost half of the cancer patients in a recent study did not receive any thromboprophylaxis during hospitalization, even though cancer and its treatment increases the risk for deep-vein thrombosis (DVT) and pulmonary embolism (PE) and three professional organizations—the American College of Chest Physicians, the American Society of Clinical Oncology, and the National Comprehensive Cancer Network—have issued guidelines recommending DVT prophylaxis.
Read More ›Decisions about prostate cancer treatment should be based on disease risk and life expectancy rather than chronologic age, according to a new analysis by University of California, San Francisco, researchers. They found that older men are more likely to have high-risk disease at diagnosis and less likely to receive potentially curative local therapy.
Use of vitamin supplements may reduce the risk of recurrence and death in women with breast cancer, two new studies suggest.
These studies contrast with some previous studies, which suggested that antioxidants may protect cancer cells during radiotherapy and chemotherapy, thus reducing the effectiveness of treatment.
More patients with chronic myeloid leukemia (CML) in chronic phase achieve molecular response when peginterferon alfa-2a is added to imatinib therapy, but toxic side effects make completing treatment difficult for many, according to analysis of SPIRIT trial data (N Engl J Med. 2010;363:2511-2521). The researchers concluded that this increase in molecular responses could translate into better survival.
Read More ›SAN ANTONIO—A re-analysis of the Women’s Health Initiative (WHI)—which found an increased risk of breast cancer and heart disease in women taking hormone replacement therapy (HRT)—suggests that estrogen alone, without progesterone, may actually be protective against breast cancer. Read More ›
SAN ANTONIO—A rapidly growing, nationwide clinical trial matching service that is user-friendly for patients is enabling more patients to learn about and enroll in clinical trials, said Ellie Cohen, PhD, the program’s director. Cohen described the success of her program at the 33rd annual San Antonio Breast Cancer Symposium. Read More ›