Novel drugs developed by UT Southwestern Medical Center researchers interrupt androgen receptor signaling
In a study conducted by a team of UT Southwestern Medical Center researchers led by Dr Ganesh Raj, associate professor of urology at UT Southwestern, tests performed in mouse and human tissue models determined that peptidomimetics, or agents designed to imitate peptides, can interrupt a cell’s androgen receptor signaling by attacking the protein in a location other than where the androgen binds, therefore impeding prostate cancer cell production.
The study is published online in Nature Communications.
Source: UT Southwestern Medical Center.