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The holiday season brings about specific pitfalls – and opportunities – for cancer survivors who desire to stay healthy throughout the season and beyond.

These tips for survivors and anyone else who wants a healthier holiday and less-stressful new year are courtesy of Karen Syrjala, Ph.D., co-director of the Fred Hutchinson Cancer Research Center Survivorship Program.

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Patients who receive chemotherapy for breast cancer may experience lingering fatigue years after their therapy, according to a follow-up study published in the American Cancer Society's recent issue of Cancer.

"Fatigue is among the most common symptoms reported by women who are treated for breast cancer," said study corresponding author Paul B. Jacobsen, Ph.D., program leader for Health Outcomes and Behavior at Moffitt.

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An independent review of the cancer research advances of 2011 was released this week by the American Society of Clinical Oncology (ASCO). The report, titled Clinical Cancer Advances 2011: ASCO’s Annual Report on Progress Against Cancer, identifies oncology trends with the most potential and provides insights from experts on the future of cancer care.

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Researchers have found that cisplatin binds 20-times more pervasively to RNA than to DNA. This makes RNA a possible new drug target for cisplatin, a compound used to fight nearly 70% of all human cancer tumors.

Although patients treated with cisplatin often experience a reduction in tumor size, use of the drug is frequently discontinued due to toxicities including anemia, gastrointestinal problems, nerve damage, renal insufficiency, and tinnitus.

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For women with HER2-positive breast cancer that has metastasized to the brain, lapatinib could prolong survival, according to research published recently in the British Journal of Cancer.

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Long-term coffee drinking may be related to a decrease in risk for endometrial cancer, according to a recent study in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Coffee is emerging as a means of defense against cancers linked to obesity, estrogen, and insulin, Edward Giovannucci, MD, ScD, professor of nutrition and epidemiology at the Harvard School of Public Health said.

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Excessive blood sugar levels are linked to an increased risk of colorectal cancer, according to a study led by researchers at Albert Einstein College of Medicine of Yeshiva University. The findings appear in a recent online edition of the British Journal of Cancer.

The study involved nearly 5000 postmenopausal women participating in the National Institutes of Health’s landmark Women’s Health Initiative study. Fasting blood sugar and insulin levels for these women were assessed at baseline and several more times during the following 12 years.

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Roche’s vismodegib has received Priority Review status, with a confirmed action date of March 8, 2012. It is aimed at the treatment of advanced basal cell carcinoma (BCC). Vismodegib is an oral medicine designed to selectively reduce signaling in the Hedgehog pathway, which is associated with more than 90% of BCC cases.

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According to a study presented at the 2011 annual meeting of the Radiological Society of North America (RSNA), women in their 40s would benefit from annual screening mammography. More specifically, women in this age group with no family history of breast cancer are just as likely to develop invasive breast cancer as women with a family history of the disease.

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More than 1 million patients receive cancer treatment in an outpatient oncology clinic each year. Unfortunately, infections from both community and healthcare settings remain a key reason for hospitalization and death among cancer patients receiving chemotherapy. In an effort to help shield this at-risk patient population, the Centers for Disease Control and Prevention (CDC) is introducing a new program that includes tools to assist both clinicians and patients in the prevention of infections.

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