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Choice of adjuvant chemotherapy based on a histocultural drug response assay (HDRA) proved useful in improving survival in patients with non–small-cell lung cancer (NSCLS) who have undergone surgical resection, according to a new study in the September issue of Journal of Thoracic Oncology.

 

Risk-reducing surgery reduced the risk for breast and ovarian cancer in a study of women with BRCA1 or BRCA2 mutations. Prophylactic salpingo-oophorectomy also reduced all-cause and cancer-specific mortality in these high-risk women.

 

Eating a variety of fruits and vegetables may protect smokers against lung cancer, according to new data from a multicenter cohort study.

 

The inverse relationship between variety in vegetable consumption and lung cancer risk was independent of quantity and restricted to current smokers.

 

The US Department of Health and Human Services has expanded coverage of evidence-based tobacco cessation counseling for Medicare beneficiaries, making it possible for all smokers to receive counseling from a qualified physician or other Medicare-recognized practitioner who can help them quit smoking.

 

Previously, Medicare covered tobacco cessation counseling only for individuals with a diagnosed tobacco-related disease or with signs or symptoms of such a disease.

 

Prostate-specific antigen (PSA) measurements at 2 years should capture the majority of low-risk cases that progress after treatment with radical prostatectomy, suggests a new study in the September issue of the Journal of Urology.

 

Adult women viewed the human papillomavirus (HPV) vaccine positively, but their decision to be vaccinated will likely be very influenced by the cost of the vaccine, according to a survey published in the August 19 issue of Sexual Health.

 

Addition of chemotherapy to radiotherapy improves survival in women with cervical cancer, results of an audit by Royal College of Radiologists suggests.

 

Dr Paul Symonds of the University of Leicester, United Kingdom, and colleagues reviewed the case histories of 1412 women with cervical cancer who were treated at 42 United Kingdom cancer centers in 2001 to 2002 (Clin Oncol. 2010;22:590-601. Epub 2010 Jul 1).They compared recurrence, survival, and complications in patients who received radiotherapy alone or combined with cisplatin.

Reduced-intensity induction therapy with a bortezomib-based regimen followed by maintenance is safe and effective for older patients with newly diagnosed multiple myeloma, a new study suggests.

 

The study by Maria-Victoria Mateos, MD, of University Hospital of Salamanca, Spain, and her colleagues, which was published online in The Lancet Oncology, showed that major responses to induction therapy were achieved in similar percentages of patients but serious toxicity was significantly reduced with less frequent dosing.

 

CT colonography (CTC) increased the odds of identifying high-risk lesions in patients undergoing colorectal cancer screening by 78%, primarily by detecting extracolonic lesions, a retrospective cohort study indicates.

 

Researchers have identified the salt inducible kinase 2 (SIK2) gene, which plays a key role in regulating the onset of cell division, as a potential target for the treatment of ovarian cancer.

 

The findings, by researchers from the University of Texas M.D. Anderson Cancer Center, Houston, add to the growing evidence that combination therapies targeting different phases of the cancer cell division cycle are needed for optimal treatment.