Web Exclusives
For the past few years, much attention has been given to the development and US Food and Drug Administration (FDA) approval of targeted oral chemotherapy agents. As our knowledge of cancer and its molecular biology increases, many targeted oral chemotherapy agents have become available for use in clinical practice. The emergence of oral chemotherapy agents has provided alternative treatment options and allowed patients to receive cancer treatment in the convenience of their home. While there are many advantages to oral chemotherapy treatment, there are also many safety concerns. Read More ›
Although an uncommon cancer, sarcoma, which can arise in various connective tissues and therefore has many subtypes, is a frightening disease for both the young and old. For example, some types of bone cancer occur primarily in children, while others affect mostly adults. As we recognize Sarcoma Awareness Week this month, let’s delve into some statistics surrounding this multifaceted cancer.
Primary bone cancer is rare and accounts for less than 0.2% of all cancers.
Read More ›It is estimated that this year alone, approximately 21,000 individuals in the United States will be diagnosed with multiple myeloma (MM), and more than 10,000 deaths will be attributed to the disease.1 Response rates and survival have improved considerably over the past several decades, due in large part to the use of high-dose chemotherapy, stem cell transplantation, and the development and approval of the targeted agents thalidomide, lenalidomide, and bortezomib.2 Although these advances have resulted in prolonged remissions and better quality of life, virtually all Read More ›
It is estimated that this year alone, approximately 21,000 individuals in the United States will be diagnosed with multiple myeloma (MM), and more than 10,000 deaths will be attributed to the disease.1 Response rates and survival have improved considerably over the past several decades, due in large part to the use of high-dose chemotherapy, stem cell transplantation, and the development and approval of the targeted agents thalidomide, lenalidomide, and bortezomib.2 Although these advances have resulted in prolonged remissions and better quality of life, virtually all Read More ›
Imagine being newly diagnosed with chronic myelogenous leukemia (CML), a neoplasm of hematopoietic stem cells caused by the Philadelphi chromosome t(9;22). In decades past, individuals diagnosed with CML were offered allogeneic hematopoietic stem cell transplant (allo-HSCT). Survival rates with allo- HSCT are lower compared with newer therapies mainly due to the risk of graft-versus-host disease and infectious complications. Read More ›
The previous installment in this cancer care series examined the growing importance of oral therapies for the treatment of cancer and the implications of patient adherence on its success. At the present time, more than 20 oral medications are approved by the Food and Drug Administration (FDA) for firstline treatment of cancer. Read More ›