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CHICAGO—Women considered at risk for breast cancer developed fewer breast cancers and fewer precursor lesions by taking the aromatase inhibitor (AI) exemestane for 5 years, versus placebo, in a large Canadian study presented at the 2011 annual meeting of the American Society of Clinical Oncology.

 

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CHICAGO—More support for bevacizumab in the treatment of ovarian cancer emerged at the 2011 annual meeting of the American Society of Clinical Oncology, with studies showing the drug prolongs the time to disease progression, both in the metastatic and primary disease settings.

 

OCEANS

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CHICAGO—More support for bevacizumab in the treatment of ovarian cancer emerged at the 2011 annual meeting of the American Society of Clinical Oncology, with studies showing the drug prolongs the time to disease progression, both in the metastatic and primary disease settings.

 

OCEANS

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CHICAGO—For the first time in decades, the treatment of advanced melanoma has taken a positive turn, according to studies presented at the 2011 annual meeting of the American Society of Clinical Oncology that showed a survival benefit with 2 experimental agents.

 

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CHICAGO—For the first time in decades, the treatment of advanced melanoma has taken a positive turn, according to studies presented at the 2011 annual meeting of the American Society of Clinical Oncology that showed a survival benefit with 2 experimental agents.

 

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CHICAGO—The oral poly (ADP-ribose) polymerase (PARP) inhibitor olaparib delayed ovarian cancer recurrence by 4 months when given as maintenance therapy to patients with platinum-sensitive relapsed ovarian cancer, in an international study reported at the 2011 annual meeting of the American Society of Clinical Oncology by Jonathan Ledermann, MD, professor of medical oncology, University College London, United Kingdom.

 

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CHICAGO—The oral poly (ADP-ribose) polymerase (PARP) inhibitor olaparib delayed ovarian cancer recurrence by 4 months when given as maintenance therapy to patients with platinum-sensitive relapsed ovarian cancer, in an international study reported at the 2011 annual meeting of the American Society of Clinical Oncology by Jonathan Ledermann, MD, professor of medical oncology, University College London, United Kingdom.

 

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ORLANDO—Three parenteral iron formulations were found to be very safe, with no anaphylactic reactions observed, in a single-center study presented at the 2010 American Society of Hematology Annual Meeting & Exposition.

The study was presented by Maureen Okam, MD, MPH, and Elyse Mandell, MSN, RNCS, of Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston.

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Orlando—Generic versions of low-molecular-weight heparin (LMWH) may not have the same efficacy and safety profile as branded products, according to investigators from Loyola University in Chicago, who presented their findings at the American Society of Hematology 2010 annual meeting (Abstract 1098).

Debra Hoppensteadt, PhD, compared several generic versions now in use outside the U.S. with enoxaparin and showed that while their molecular weight distributions were mostly similar, each of the products exhibited its own specific pharmacologic profile.

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ANAHEIM—Hypersensitivity or infusion reactions to chemotherapy agents or monoclonal antibodies can be life-threatening but often can be managed with premedications or titration of infusion rates to allow continuance of therapy, said Catherine Christen, PharmD, at the 45th American Society of Health-System Pharmacists Midyear Clinical Meeting & Exposition.

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