Articles
A younger woman’s risk of an aggressive form of breast cancer may be reduced by up to 60% if she waits at least 15 years following her first menstrual period to give birth to her first child.
Immediate or near-term risk of death from the patient’s condition should be taken into account when weighing the benefits of an imaging exam against a potential future risk of radiation-induced cancer from the imaging.
The tumors of patients with a family history of colorectal cancer often carry a molecular sign that the cancer could be life threatening and may necessitate aggressive treatment.
When treating early breast cancer, a lower total dose of radiotherapy, provided in fewer, larger treatments, is as safe and effective as the international standard dose, according to the 10-year follow-up results of a major trial.
Researchers use a new method to identify potential anticancer drug combinations.
Carfilzomib (Kyprolis, Onyx Pharmaceuticals, Inc, South San Francisco, CA) is a selective proteasome inhibitor that irreversibly binds to active sites within the proteolytic core of the 26S proteasome, resulting in inhibition of proteasome activity. Preclinical studies have shown carfilzomib inhibits tumor growth and promotes tumor cell death, with sustained proteasome inhibition for more than 48 hours when using a consecutive-day dosing regimen.1-4
ES has received 5 prior lines of therapy, with progression of disease documented on her most recent therapy with a rise in SPEP from 1.3 to 2.2 g/dL and in UPEP from 556 to 1342 mg/24 hours. The current clinical considerations include anemia, renal insufficiency, and PN grade 1 with pain.
New study results show that patients who consumed more than 4 cups of caffeinated coffee per day had half the risk of death of oral/pharyngeal cancers compared with those who only occasionally or never drank coffee.
Medication reconciliation is a complex and cooperative clinical task required of physicians, nurses and pharmacists in which the goal is to minimize discrepancies and inappropriate medication orders.