Articles
Reduced-intensity induction therapy with a bortezomib-based regimen followed by maintenance is safe and effective for older patients with newly diagnosed multiple myeloma, a new study suggests.
The study by Maria-Victoria Mateos, MD, of University Hospital of Salamanca, Spain, and her colleagues, which was published online in The Lancet Oncology, showed that major responses to induction therapy were achieved in similar percentages of patients but serious toxicity was significantly reduced with less frequent dosing.
CT colonography (CTC) increased the odds of identifying high-risk lesions in patients undergoing colorectal cancer screening by 78%, primarily by detecting extracolonic lesions, a retrospective cohort study indicates.
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Researchers have identified the salt inducible kinase 2 (SIK2) gene, which plays a key role in regulating the onset of cell division, as a potential target for the treatment of ovarian cancer.
The findings, by researchers from the University of Texas M.D. Anderson Cancer Center, Houston, add to the growing evidence that combination therapies targeting different phases of the cancer cell division cycle are needed for optimal treatment.
SAN DIEGO – Cancer patients at high risk for bone loss due to their disease or its management may want to go easy on the diet cola consumption. New data presented at the Endocrine Society’s 92nd annual meeting and expo suggest that drinking diet colas on a regular basis may be associated with a decrease in bone mineral density (BMD) and an increased fracture risk.
SAN DIEGO—Cancer patients at high risk for bone loss due to their disease or its management may want to cut down on the diet cola consumption. New data presented at the Endocrine Society’s 92nd annual meeting and expo suggest that drinking diet colas on a regular basis may be associated with a decrease in bone mineral density (BMD) and an increased fracture risk.
SAN FRANCISCO—Italian researchers have found that delivering a single dose of intravesical chemotherapy preoperatively may be a better approach than postoperative chemotherapy for improving a patient’s risk of recurrence of non–muscle invasive bladder cancer (NMIBC).
SAN FRANCISCO—Italian researchers have found that delivering a single dose of intravesical chemotherapy preoperatively may be a better approach than postoperative chemotherapy for improving a patient’s risk of recurrence of non–muscle invasive bladder cancer (NMIBC).
Early Palliative Care Improves Quality of Life, Increases Survival in Patients with Metastatic NSCLC
Patients with metastatic non–small-cell lung cancer (NSCLC) who received early palliative care as well as standard care had a better quality of life (QoL), improved mood, and, despite receiving less aggressive end-of-life care, lived longer than patients who received standard care alone, a new study shows.
In women with BRCA mutations, increased mammographic breast density is not associated with a higher risk of breast cancer and should not be a factor in making decisions about treatment, Canadian researchers report.
Increased mammographic breast density is a known breast cancer risk factor in the general population but it was not known whether that would hold true in women with BRCA1 or BRCA2 mutations.
A novel prognostic model makes it possible to stratify the majority of elderly patients with acute myeloid leukemia (AML) into two prognostic groups with significant implications for the therapeutic strategy.
As reported in the August issue of Blood, use of the additive model, which integrates the well-established cytogenic risk system, allowed stratification of elderly AML patients with intermediate-risk karotype into good intermediate risk and adverse intermediate risk groups with distinctly different prognoses.