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Exercise programs should be initiated more widely among established androgen-deprivation therapy (ADT) users, argue the results of a new study by researchers at the University of Toronto. In addition, their study highlights the importance of further investigation into whether initiating exercise at the same time as that of ADT can reverse or prevent the negative physical outcomes often associated with ADT.
Adjuvant trastuzumab treatment may be beneficial for women with small human epidermal growth factor receptor 2 (HER2)-positive breast tumors, according to a review by British researchers.
Approximately half of colorectal and cervical cancer cases and one third of breast cancer cases are still diagnosed at a late stage of disease, according to a Surveillance Summary released by the US Centers for Disease Control and Prevention (CDC) in the November 26 issue of Morbidity and Mortality Weekly Report.
Endosonography combined with surgical staging has greater sensitivity for detecting mediastinal nodal metastases, according to results of a randomized, controlled trial published in the November 24 issue of JAMA.
Errors in clinical staging of localized prostate cancer occur frequently, particularly when transrectal ultrasound (TRUS) is used to detect abnormalities, a new study suggests.
The study showed that in more than a third of cases, the cancer staging assignment was incorrect, casting doubt on the utility of a staging system for localized prostate cancer based on digital rectal examination (DRE) and TRUS.
Using a cough suppressant syrup as a probe could help physicians determine how well an individual breast cancer patient metabolizes tamoxifen, according to a study presented at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Berlin. This would enable physicians to identify patients with altered metabolism and use this information to personalize treatment, making it more effective and reducing the risk of side effects, the researchers say.
The US Food and Drug Administration this week approved denosumab (XGEVA, Amgen) for prevention of skeletal-related events (SREs) in patients with bone metastases from solid tumors. Also this week, approval was granted for eribulin mesylate injection (Halaven, Eisai) for treatment of metastatic breast cancer.
Denosumab
Read More ›Treating patients with advanced hepatocellular carcinoma (HCC) with a combination of doxorubicin and sorafenib may increase median time to progression, overall survival, and progression-free survival compared with doxorubicin alone, a new study suggests.
A multidisciplinary clinic approach is the key to successful treatment of aggressive, locally advanced prostate cancer, according to researchers from the Kimmel Cancer Center (KCC) of Thomas Jefferson University, Philadelphia.
Results of the first open-label study comparing romiplostim treatment with standard- of-care therapies in nonsplenectomized adult patients with chronic immune thrombocytopenia (ITP) show that both the incidence of treatment failure and need for splenectomy were reduced among romiplostim-treated patients.