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Adding chemotherapy to radiotherapy (RT) for muscle-invasive bladder cancer is well tolerated and improves loco-regional disease-free survival (LRDFS) compared with RT alone, according to a study presented at the 52nd Annual Meeting of the American Society for Radiation Oncology (ASTRO).
The US Food and Drug Administration (FDA) has approved dasatinib (Sprycel, Bristol-Myers Squibb) 100 mg once daily for the treatment of adult patients with newly diagnosed Philadelphia chromosome–positive (Ph+) chronic myeloid leukemia (CML) in chronic phase.
A study by Virginia Commonwealth University Massey Cancer Center researchers showed that most terminally ill cancer patients who were eligible for genetic testing did not receive it even though it could potentially save a relative's life.
The research, reported by John M. Quillin, PhD, and associates in the October issue of the Journal of Genetic Counseling, is the first to document the prevalence of hereditary cancer risk and the need for genetic services and patient education among terminally ill cancer patients.
Patients with metastatic colorectal cancer (CRC) who have KRAS –mutated tumors are currently excluded from treatment with the antiepidermal growth factor monoclonal antibodies cetuximab and panitumumab. A new study, however, suggests that patients with a KRAS codon 13 mutation have better outcomes when treated with cetuximab than patients with other KRAS mutations.
An updated clinical practice guideline issued by the American Society of Clinical Oncology and the American Society of Hematology provides detailed recommendations on use of the erythropoiesis-stimulating agents (ESAs) epoetin and darbepoetin in adults with cancer-induced anemia.
The guideline, which updates the 2007 guideline, states that these agents should be avoided in patients who are not receiving concurrent chemotherapy, except for those with lower-risk myelodysplastic syndromes.
Patient adherence to colorectal cancer (CRC) screening guidelines remains suboptimal, particularly among minorities. Two new studies suggest ways to increase screening rates.
One study, by Moshe Shike, MD, of Memorial Sloan-Kettering Cancer Center, New York, and associates found that offering CRC screening during mammography visits is “an effective way of generating interest and initiating the process” in minority women. The results are reported online in Cancer.
A new intervention designed to help mothers cope with the stresses associated with their child’s cancer appears to be more effective long term compared with other psychological approaches, according to a study reported at the 42nd Congress of the International Society of Pediatric Oncology.
Patients with chronic myeloid leukemia (CML) who have maintained complete molecular remission (CMR) for at least 2 years can safely discontinue imatinib therapy, French researchers report.
Many patients diagnosed with skin cancer do not know whether they have melanoma or nonmelanoma skin cancer and, as a result, may have a poor sense of the measures they need to take to reduce the risk of future skin cancers, a study by an investigator at The Cancer Institute of New Jersey, New Brunswick, indicates.
In a long-term study of men who underwent robot-assisted radical prostatectomy (RARP) nearly 87% had no recurrence of the disease after 5 years.
The study cohort included 1384 men who were diagnosed with moderately aggressive localized prostate cancer and underwent RARP between September 2001 and May 2005 at a tertiary center. Their average age was 60 years.